Trauma | Hemorrhage and Shock

Hemorrhage and Shock

Perfusion: The process by which oxygenated blood is delivered to the body tissues and wastes are removed.
Diffusion: movement of particles from an area of greater concentration to an area of lesser concentration.

Fick Principle: the quantity of O2 delivered to a body organ is equal to the amount of O2 consumed by the organ plus the amount carried away. There are four necessary components to get O2 to the cells:

  1. Inspiration of adequate O2 in air, no blockage in airways
  2. On-loading O2 to RBCs at the lungs, adequate numbers of RBCs, and good capillary/alveoli contact
  3. Delivery of RBCs to the tissue cells, adequate pump and fluid to flow
  4. Off-loading O2 from RBC to tissue cells, good capillary contact, pH balance and temperature

Cellular Metabolism: aerobic=with air=allows body to use food for energy more efficiently

  • Cellular respiration = food (glucose) being broken down for energy in a series of reactions
  • By product produced = pyruvic acid. In low O2 states, this is converted to lactic acid
  • O2 plays role in preventing accumulation of lactic acid

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